Yes, Ara features numerous options designed to make the game more accessible. Some significant options are presented upon first launch of the game, but all of these can be found on the Accessibility menu of the Settings screen.
The game supports both Text and UI Scaling as well as an option for High Contrast Text.
Ara is also compatible with the Windows Accessibility Color Filter feature, as well as Narration. If you have the Screen Narration option selected in game but do not hear any narration, please ensure that Narration is enabled in Windows.